Introductory
- The Chemistry NMR facility no longer provides licenses to Bruker’s TopSpin processing software, as it is now free for academic users. Go to Bruker’s website for the license and download.
- The guides listed below are all for Bruker Avance consoles running TopSpin 3.0 or newer, except for one area in the Misc section.
- One-Sheet Acquisition Step-by-Step
- Data Archiving to Castor
- ICON NMR training (video)
- Automation using IconNMR and the SampleJet Robot
- Use of the SampleCase Robot
- Stopping IconNMR queue on Eos
Guides
1D NMR
- Common 1D NMR experiments using IconNMR
- Directly-detected 1D X-nucleus experiments (13C, 31P, 19F, 29Si, etc) in TopSpin
— Notes for Boron(11B and 10B) NMR - Pulsewidth calibrations in TopSpin
- T1 estimates using TopSpin
- Accurate T1 measurements using IconNMR
- Selective 1D experiments (eg, noesy1d, tocsy1d)
Miscellaneous
More TopSpin 3.x Guides
- Running IconNMR in Individual Topspin sessions
- Non-Uniform Sampling (NUS)
- Setting up 19F adiabatic decoupling
- CMC-se and CMC-assist Notes (Structure Elucidation & Structure Verification)
Other/Older Bruker Guides
2D NMR
- 2D NMR via TopSpin: cosy, cosylr, dqfcosy, tocsy, hsqc, hsqc-edited, hsqc-coupled, hmbc, noesy, roesy
- 2D NMR via IconNMR
— cosy, cosylr, dqfcosy
— tocsy, hsqc
— hmbc
More Exps
- no-D 1H and 13C NMR (use of non-deuterated solvents)
- 2H (deuterium) NMR
- Solvent Suppression -> (new: LC-NMR solvsup)
- Variable Temperature NMR
- Monitoring Kinetics by NMR
- DOSY/Diffusion in TopSpin 3.x
- Ligand Binding:
— Saturation-Transfer Difference (STD)
— CPMG - Chemical Exchange Saturation Transfer (CEST) NMR
- 13C T1 values from HC-hsqc